
TrueMed Vitamin D3 & K2 – 120 Vegetarian Capsules, 5000 IU D3 + 90 mcg K2 MK-7 Per Capsule
About The Product

TrueMed Vitamin D3 & K2 delivers a high-potency pairing of Vitamin D3 (Cholecalciferol, 5,000 IU / 125 mcg) and Vitamin K2 as MK-7 (Menaquinone-7, 90 mcg) in a single vegetarian capsule. These two fat-soluble vitamins are among the most complementary nutrient partners in clinical nutrition — their combined action on calcium metabolism creates synergistic benefits for bone health, cardiovascular protection, and immune function that neither vitamin achieves as effectively when taken alone.
Vitamin D3 (Cholecalciferol) is the form of Vitamin D synthesized by the skin upon sun exposure and is the most bioavailable oral supplemental form. It dramatically increases intestinal calcium and phosphorus absorption — but without Vitamin K2, this increased calcium must be managed by the body to prevent arterial deposition. Vitamin K2 as MK-7 is the solution: it activates two critical proteins — Osteocalcin (which incorporates calcium into bone) and Matrix Gla Protein, or MGP (which removes calcium from soft tissues and arteries). At 5,000 IU per capsule with 120 capsules per bottle, TrueMed D3 & K2 provides a 4-month supply at the standard daily dose — making it one of the best value vitamin D3 K2 combinations available. Produced in a GMP-certified, FDA-registered USA facility by TrueMed Pharma Inc.
- Vitamin D3 as Cholecalciferol 5,000 IU (125 mcg): The biologically active form of Vitamin D — increases intestinal calcium absorption from ~10–15% (baseline) to 30–40%, supporting the calcium availability needed for bone mineralization, immune cell function, and cellular processes.
- Vitamin K2 as MK-7 (Menaquinone-7) 90 mcg: The long-acting form of K2 (half-life ~72 hours vs MK-4’s 1–2 hours) — activates Osteocalcin to bind calcium into the bone matrix and activates MGP to protect arterial walls from calcium deposition.
- Osteocalcin & MGP Activation: The two Vitamin K2-dependent proteins responsible for calcium direction — Osteocalcin drives calcium into bone; MGP (Matrix Gla Protein) removes calcium from arterial and soft tissue walls, protecting vascular flexibility.
- No Competing Fillers: Just Rice Flour and Cellulose capsule — clean, minimal excipients appropriate for a fat-soluble vitamin formula.

Vitamin D3 Intestinal Calcium Absorption Amplification
Cholecalciferol supports active calcium transport in the small intestine through VDR (Vitamin D Receptor)-mediated upregulation of TRPV6 and calbindin-D9k transporter proteins, dramatically increasing intestinal calcium absorption efficiency.

K2 MK-7 Osteocalcin Carboxylation & Bone Calcium Incorporation
MK-7 activates osteocalcin carboxylation, enabling this bone matrix protein to bind calcium ions and incorporate them into the hydroxyapatite crystal lattice of bone — translating increased calcium availability into measurable bone density gains.
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Matrix Gla Protein (MGP) Activation & Vascular Calcification Inhibition
MK-7 carboxylates Matrix Gla Protein in arterial walls, activating the body’s primary endogenous inhibitor of vascular calcification — protecting arterial flexibility, reducing coronary calcium score risk, and addressing the cardiovascular dimension of calcium metabolism that D3 supplementation alone does not cover.

VDR-Mediated Immune Modulation & Cellular Gene Regulation
Vitamin D3’s active form (calcitriol) acts on Vitamin D Receptors expressed on immune cells, supporting balanced innate and adaptive immune activity, antimicrobial peptide production, and the regulation of over 1,000 vitamin D-responsive genes across multiple organ systems.



Strong Bones. Healthy Arteries. Resilient Immunity. — One Capsule, Daily.
TrueMed Vitamin D3 & K2 brings together two of the most evidence-supported micronutrients in clinical nutrition — not as separate supplements requiring coordination, but as a single daily capsule designed to work as nature intended. Vitamin D3 at 5,000 IU drives the calcium absorption that bones and cells depend on; Vitamin K2 MK-7 at 90 mcg ensures that calcium goes where it belongs — into bone matrix, not arterial walls. The result is comprehensive support for bone density, cardiovascular calcium protection, and immune system function from one clean, simple daily capsule. 120 capsules per bottle, four months of daily support, vegetarian, non-GMO, gluten-free — produced in a GMP-certified USA facility by TrueMed Pharma Inc.
