TrueMed Vision Support II is a 6-nutrient daily eye health formula designed to mirror the nutrient combination studied in the AREDS2 (Age-Related Eye Disease Study 2) — the landmark National Eye Institute clinical research program that provided the most rigorous nutritional evidence ever generated for macular eye health. The formula delivers Vitamin C (500 mg), Vitamin E (180 mg), Zinc (25 mg), Copper (2 mg), Lutein (10 mg, from Marigold Flower Extract), and Zeaxanthin (2 mg, from Marigold Flower Extract) in a 2-caplet daily serving across 90 days.

The AREDS2 study — conducted by the NIH across multiple sites with thousands of participants over five years — demonstrated that this nutrient combination reduced the risk of progression to advanced AMD by approximately 25% in individuals with intermediate AMD or advanced AMD in one eye. AREDS2 updated the original AREDS formula by replacing beta-carotene with Lutein and Zeaxanthin after finding the macular carotenoids provided superior benefit with a better safety profile (beta-carotene increases lung cancer risk in smokers). TrueMed Vision Support II uses this AREDS2-updated formulation — and critically includes Copper (2 mg) alongside the high zinc dose, as AREDS2 itself does, to prevent the copper deficiency that prolonged high-dose zinc supplementation can otherwise cause. With 180 caplets providing a 90-day supply, Vision Support II is designed for the long-term, consistent daily supplementation that eye health evidence recommends. Produced in a GMP-certified, FDA-registered USA facility by TrueMed Pharma Inc.

1. Vitamin C 500 mg (Ascorbic Acid, 556% DV): Replenishes the aqueous humor’s extraordinary antioxidant demand (ascorbate concentration 25× plasma levels), supports corneal collagen integrity, and protects the anterior eye from oxidative damage.
2. Vitamin E 180 mg (DL-Alpha Tocopheryl Acetate, 1,200% DV): Protects DHA-rich photoreceptor outer segment lipid membranes from light-induced lipid peroxidation in the retina’s highest-oxidative-stress environment.
3. Zinc 25 mg (Zinc Oxide, 227% DV): Essential cofactor for retinol dehydrogenase and other retinal pigment epithelium enzymes involved in the visual cycle, rhodopsin regeneration, and Vitamin A metabolism in ocular tissue.
4. Copper 2 mg (Cupric Oxide, 222% DV): Prevents the copper deficiency caused by prolonged high-dose zinc supplementation — protecting copper-dependent superoxide dismutase activity and preventing anemia from zinc-copper competition at intestinal absorption.
5. Lutein 10 mg from Marigold Flower Extract: Primary macular carotenoid accumulating throughout the macular pigment — blue light filtration and antioxidant quenching in the peripheral macula.
6. Zeaxanthin 2 mg from Marigold Flower Extract: Foveal carotenoid found at highest concentration in the fovea alongside Lutein at the naturally occurring 5:1 macular ratio.